Coal mining has majorly caused deteriorative environmental changes in East Kalimantan, in which severely affects wild bee habitat. Stingless bee is a group of bee that is received the least attention in Indonesia. Samarinda Botanical Garden, East Kalimantan, Indonesia, is overwhelmed by improper exploitation of coal mining that surrounds the garden, a natural habitat for stingless bee. Products from stingless bee are scientifically less explored and many contain specific compounds which have never been found in other species of bee. We have collected propolis, bee pollen, and honey from four species of stingless bees that have been previously identified in the botanical garden, which are Trigona incisa, T. apicalis, T. fuscibisca and T. fuscobalteata. Products were then extracted with methanol. The crude extracts were tested in vitro at a concentration of 20 µg/ml against colon cancer (SW620) and breast cancer (BT474) cell lines. Phytochemical tests for the early detection classification of compounds in the bee products were carried out after further extraction with MeOH. MeOH extract of T. incisa propolis had the highest effect on SW620 (Ps 8 %) and that of T. apicalis propolis against BT474 (Ps 28 %). Products of stingless bee contain alkaloids, flavonoids, carbohydrates and tannins. The results may indicate that the stingless bee products from the botanical garden have potential cancer treatment. Preserving stingless bee habitat such as in Samarinda Botanical Garden is highly recommended with regard to exploration of promising biodiversity potency for pharmacotherapy from bees in East Kalimantan. Further, research in phylogenetic may uncover the more significant contribution of stingless bees.

Keywords : stingless bee, bee products, phytochemical test, botanical garden